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3916a sinemet 25-100 tablets are yellow, round, uncoated tablets, that are coded 650 on one side and plain on the other.
Information about Sinemet.
Because both therapeutic and adverse responses occur more rapidly with SINEMET than with levodopa alonepatients should be monitored closely during the dose adjustment periodSpecificallyinvoluntary movements will occur more rapidly with SINEMET than with levodopaThe occurrence of involuntary movements may require dosage reductionBlepharospasm may be a useful early sign of excess dosage in some patients.
Do not be alarmed by this list of possible side effectsYou may not experience any of them.
Carbidopa allows patients treated for Parkinson’s disease to use much lower doses of levodopaSome patients who responded poorly to levodopa have improved on SINEMETThis is most likely due to decreased peripheral decarboxylation of levodopa caused by administration of carbidopa rather than by a primary effect of carbidopa on the nervous systemCarbidopa has not been shown to enhance the intrinsic efficacy of levodopa.
Tell your doctor if you are taking any other medicinesincluding any that you buy without a prescription from your pharmacysupermarket or health food shopSome medicines and SINEMET may interfere with each otherThese include:
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do not give sinemet to a child or teenager below the age of 18, unless advised by the child s doctor.